CBD oil for headaches

Today, we will explore how CBD products are emerging as an effective therapeutic alternative for all those suffering from headaches. Its analgesic, anti-inflammatory and sedative properties, which act both physically and psychologically, position CBD as a crucial tool not only to mitigate the symptoms linked to migraines, but also to attenuate their regularity and/or severity in a consistent manner and bring about a notable improvement in quality of life.

CBD and headaches

In an exhaustive review conducted by Ethan Russo, which traces the history of the use of cannabis to alleviate headaches, it is detailed how this plant has been used for centuries in the symptomatic therapy of migraines and headaches in various cultures, from Islamic, Indian, Chinese, to Greek and Roman. Specifically, between 1842 and 1942, it was a fundamental component of Western pharmacopoeias, being considered the remedy of choice by preeminent physicians to deal with migraine symptoms.

Today, recent advances on the Endocannabinoid System have allowed a greater understanding of the mechanisms inherent to headaches and the role that phytocannabinoids could play in each particular case, especially CBD.

Due to scientific findings in recent years, a direct relationship between the mechanisms that can trigger headaches and migraines and the Endocannabinoid System (ECS) in particular has become evident:

• The activation of cannabinoid receptors (CB1 and CB2) and vanilloid receptors (TRPV) enables the activation of the anti-inflammatory mechanisms of our organism and provides an analgesic effect.
• The ECS regulates the serotonergic (serotonin) and dopaminergic (dopamine) systems and interacts with the mechanisms of action of triptans and opioid pathways, playing a crucial role in the neuronal transmission of pain.
• Individuals suffering from chronic migraines show a marked decrease in the levels of Anandamide and 2-AG (the primary endocannabinoids) and also a considerable increase in FAAH enzymes (those that degrade endocannabinoids).

These studies seem to support the hypothesis suggesting that disorders such as migraines could have their origin in an ECS dysfunction, highlighting how a therapy focused on indirect stimulation of endocannabinoids (through FAAH inhibition) seems very promising, which places CBD in a position of relevance.

Effects of CBD on headache pain

Although specific clinical trials on the use of CBD to treat migraines have not yet been conducted, much of the available human clinical evidence is based on single case or small group studies, as well as anecdotal accounts and surveys.

However, thanks to current advances in research into the properties of CBD and the relationship between the Endocannabinoid System and the mechanisms of action of migraines and headaches, it has been found that Cannabidiol could offer even greater efficacy.

Effects of CBD on headaches/migraines

CBD is proving to be a valuable tool in the treatment of headaches and their associated symptoms, thanks to its outstanding properties:

• Its anti-inflammatory and analgesic capacity is essential to alleviate discomfort.
• At the physical level, it has relaxing properties, especially at the muscular level.
  At the mental level, it acts as a relaxant, helping to improve mood.
• In addition, its modulating action on the Endocannabinoid System allows an indirect increase in the levels of our own endocannabinoids.

However, it should be noted that headaches and migraines, although sharing the main symptom of headache, are usually caused by different mechanisms. Therefore, recommendations and routes of administration may vary according to each particular case.

How to use CBD oil for headaches

Dosage

It is crucial to keep in mind that CBD is a natural compound that interacts with other physiological systems, adapting to the needs of the organism to restore its balance in a natural and sustainable way. This implies, mainly, that a higher quantity does not guarantee a more intense or beneficial effect.

Therefore, there is an optimal dosage for each person, which can be discovered by starting with a minimum amount (about 10 mg of CBD divided into three daily intakes) and gradually increasing (for example, adding about 10 mg of CBD every two or three days, depending on the response) until the desired effect is perceived. It is important to keep in mind that once the right dosage is found, it will remain relatively stable over time, since CBD does not generate tolerance, i.e., it is not necessary to increase the dose over time to obtain the same effects.

In any case, it is always advisable to consult a specialist who can provide follow-up, advise on quality products (since the market is not regulated in Spain) and provide information on the legal framework corresponding to the country of residence.

Route of administration

In Spain it can only be applied topically. It should be massaged gently on the neck, forehead and temples when necessary or preventively up to a maximum of 3-4 times a day. Its effect is limited to the area of application and can provide a remarkable relief of symptoms, favoring muscle relaxation.

Is it safe to use?

According to the studies conducted to date, it has been confirmed that CBD does not have toxic properties, even when administered over a long period of time or in high doses. If you would like to learn more about the subject, we recommend you consult our article about the report issued by the WHO on the use of Cannabidiol. In this document you will find detailed information backed by scientific evidence about the non-toxic properties of CBD, which provides greater peace of mind and security to those considering its use.

Bibliography

• Baron, E. P. (2018). Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: An update on current evidence and cannabis science. Headache: The Journal of Head and Face Pain, 58(7), 1139-1186.
• Russo, E. B. (2016). Clinical endocannabinoid deficiency reconsidered: Current research supports the theory in migraine, fibromyalgia, irritable bowel, and other treatment-resistant syndromes. Cannabis and Cannabinoid Research, 1(1), 154-165.
• Akerman, S., Holland, P. R., & Goadsby, P. J. (2013). Cannabinoid (CB1) receptor activation inhibits trigeminovascular neurons. Pain, 154(11), 2750-2758.
• Silberstein, S. D. (2020). The role of cannabinoids in headache disorders. Headache: The Journal of Head and Face Pain, 60(4), 885-890.
• Department of Health and Human Services. National Institutes of Health. National Center for Complementary and Integrative Health (n. d.). Cannabis (Marijuana) and Cannabinoids: What You Need To Know.